In Vitro fertilisation (IVF) of the eggs can be performed through conventional IVF, intracytoplasmic sperm injection (ICSI) or intracytoplasmic morphologically selected sperm injection (IMSI).
Find out how the egg retrieval process is performed.
Conventional fertilisation consists of connecting the eggs with more than 100,000 sperm so that fertilisation occurs.
When is conventional fertilisation recommended?
Conventional fertilisation has been the technique used for IVF until the appearance of ICSI. Currently its use is limited to those rare cases in which fertilisation can be performed with both techniques if there is a high number of eggs.
What is ICSI?
ICSI consists of the intracytoplasmic sperm injection technique. One sperm is injected into each egg through microinjection. Sperm selection is performed at 400x magnification.
When is the ICSI treatment recommended?
ICSI is the most common In Vitro fertilisation technique of choice for the majority of cases, especially if there has been a history of fertilisation failure or very poor sperm quality.
Learn about the intracytoplasmic sperm microinjection technique.
IMSI consists of the intracytoplasmic injection of morphologically selected sperm. It differs from ICSI in that sperm selection is performed under 8000x, which allows the best sperm to be chosen, significantly improving the reproductive prognosis.
In order to perform it, a microscope with high image quality combined with complex computer software is needed, which allows the handling of the microscope from their computer.
When is the IMSI method recommended?
Applying IMSI is recommended in cases of poor sperm quality, to improve the selection of the sperm that will be used when fertilising the egg:
Severe teratospermia
High levels of sperm DNA fragmentation
These are the differences between ICSI and IMSI techniques.
We were on the IVF journey, four years and two attempts later, we decided to follow our doctor's recommendation and seek treatment in Barcelona. We visited several clinics but chose Barcelona IVF after thorough research…
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We were on the IVF journey, four years and two attempts later, we decided to follow our doctor's recommendation and seek treatment in Barcelona. We visited several clinics but chose Barcelona IVF after thorough research and meeting our doctor. Dr. Rose is a very attentive, dedicated doctor who loves what she does and is highly qualified. Her team is also very attentive, especially Elena, who supported us throughout the treatment, and that reassurance made all the difference. Thank you so much, Dr. Rose, for helping us realize our dream of motherhood. I have no words to express how grateful we are to have our beautiful and healthy son in our arms. We recommend the clinic to everyone.
★★★★★
We had a very positive experience with Barcelona IVF throughout our fertility journey. The team was professional, supportive, and caring, and they helped guide us through what can be an emotional process. We felt well…
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We had a very positive experience with Barcelona IVF throughout our fertility journey. The team was professional, supportive, and caring, and they helped guide us through what can be an emotional process. We felt well informed and looked after every step of the way. Most importantly, our journey had a wonderful outcome — we were blessed with a healthy baby girl. We are incredibly grateful for the care and support we received and would recommend Barcelona IVF to others beginning their fertility journey.
★★★★★
Our experience with Barcelona IVF has been truly exceptional from beginning to end. After two successful IVF treatments, we are now the proud parents of a beautiful daughter and a wonderful son. Words cannot fully…
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Our experience with Barcelona IVF has been truly exceptional from beginning to end. After two successful IVF treatments, we are now the proud parents of a beautiful daughter and a wonderful son. Words cannot fully express how grateful we are to the entire team for helping us achieve our dream of building our family. The professionalism, expertise, and dedication of every doctor, nurse, coordinator, and staff member were outstanding. Throughout the entire process, we felt supported not only medically but also emotionally and psychologically. The team was always available to answer our questions, guide us through every step, and provide reassurance whenever we needed it. What makes Barcelona IVF truly special is the warm, caring, and welcoming environment they create for their patients. From the very first consultation, we felt respected, understood, and genuinely cared for. We will always be thankful to Barcelona IVF for changing our lives and giving us the greatest gifts we could ever ask for—our two beautiful children. We wholeheartedly recommend Barcelona IVF to anyone looking for a fertility clinic that combines world-class medical care with compassion and humanity. Thank you for everything. You will always hold a special place in our hearts.
★★★★★
From the very first moment, we felt we were in safe and caring hands. This journey wasn’t easy, but your entire team made it feel supported, understood, and full of hope. The doctors were not only highly skilled but…
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From the very first moment, we felt we were in safe and caring hands. This journey wasn’t easy, but your entire team made it feel supported, understood, and full of hope. The doctors were not only highly skilled but also incredibly kind and reassuring—they gave us confidence when we needed it the most. And to the reception and support staff, thank you for your warmth and constant support—you truly made all the difference. Today, we are overjoyed and deeply grateful to share that we are pregnant. This happiness is because of you. Thank you for helping us create our dream. With all our gratitude Neelam and Zoraver 🙂✨
★★★★★
Thanks to Dr Zamora and the entire medical staff, our beautiful baby daughter was born recently, healthy and beautiful, we are happy parents. The staff mostly speaks English so its foreigner friendly, they treat you…
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Thanks to Dr Zamora and the entire medical staff, our beautiful baby daughter was born recently, healthy and beautiful, we are happy parents. The staff mostly speaks English so its foreigner friendly, they treat you with utmost respect and most importantly the whole process was efficient, we got pregnant on our very first round, so yes it’s possible to succeed on your first trial.
★★★★★
The most wonderful clinic, full of kind and brilliant people. How lucky we are to have come to this place and our two sons would definitely agree. 100% recommend.
★★★★★
I got the contact of this clinic from a friend and we had a great experience. At the beginning it was unusual to have remote contact with the assistance person but it’s a great opportunity for people like us not living…
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I got the contact of this clinic from a friend and we had a great experience. At the beginning it was unusual to have remote contact with the assistance person but it’s a great opportunity for people like us not living in Barcelona. All the staff is professional and helpful, and knows how to deal with the stress of the situation. The doctor was great and waited to have the results of all exams required before giving a diagnosis and suggesting the way forward. What was prosed was meaningful and very professional. It was absolutely NOT an attempt to get more money from you. Highly recommended.
★★★★★
American single mom by choice here. Writing to express my sincerest gratitude for Barcelona IVF! I had tried and failed a full round of IVF in Germany. Those drs told me I needed a bunch of expensive tests though I had…
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American single mom by choice here. Writing to express my sincerest gratitude for Barcelona IVF! I had tried and failed a full round of IVF in Germany. Those drs told me I needed a bunch of expensive tests though I had no observable fertility issues. When I switched to BIVF, I got pregnant pretty much immediately. See photo of my 4 month old here!! I was treated with kindness and respect despite having a somewhat pushy and suspicious attitude due to my previous experiences. I can’t thank BIVF enough for helping me achieve the family I always wanted. I live in the US now and recommend BIVF to everyone I encounter here hoping to conceive. Even with the expensive plane tickets, the prices are far more reasonable than US costs. Gracias!
★★★★★
Our IVF journey started in September 2025. We started with one Dr but I made the decision to change Doctors. Ultimately, I made the right decision because with Dr Zamora, I felt safe and well taken care of from the…
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Our IVF journey started in September 2025. We started with one Dr but I made the decision to change Doctors. Ultimately, I made the right decision because with Dr Zamora, I felt safe and well taken care of from the moment we had our meeting with him. I trusted him 100% that he will get my wife pregnant. While I did egg collection and injections, he implanted our embryo on my wife. During egg collection, I felt so relaxed and had no pain at all post egg collection. My wife has been having a good pregnancy as the symptoms have been general pregnancy symptoms. We are so grateful and thankful to Dr Zamora for making the right decisions for medication for me and embryo transfer for my wife. And forever thankful to Medical Assistant, MAEV for all the guidance, support and empathy she showed us. We are finishing the first trimester and feel confident that baby will continue to grow until we meet him/her soon. THANK YOU AGAIN BARCELONA IVF. We look forward to making second baby with you soon.
★★★★★
We had an incredible experience and everyone has threaten me with such empathy and respect during a process that it can be sometimes challenging. In the end we had our little baby angel girl and we can't be more…
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We had an incredible experience and everyone has threaten me with such empathy and respect during a process that it can be sometimes challenging. In the end we had our little baby angel girl and we can't be more grateful to Dr.Zamora and the whole team.
★★★★★
Excellent clinic with a wonderful team. The facility is beautiful, and the entire medical staff is incredibly supportive and responsive. Thanks to their expertise and care, I am now holding my beautiful baby girl in my…
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Excellent clinic with a wonderful team. The facility is beautiful, and the entire medical staff is incredibly supportive and responsive. Thanks to their expertise and care, I am now holding my beautiful baby girl in my arms.
★★★★★
Great and succssful experience! Super recommended to everybody! Communication was easy and care was excellent! Thank you very much for your help!
