What Results Does an Endometrial Receptivity Test Provide, And How Long Does It Take?

The Endometrial Receptivity Test, known as ERA (Endometrial Receptivity Array), measures the expression of genes associated with endometrial receptivity. The goal of this test is to determine the optimal time when the endometrium is most receptive to embryo implantation—this is known as the “implantation window.” The results are usually available approximately 20 days after the endometrial biopsy.

The possible ERA test results are:

• Receptive: The implantation window is not displaced, and the gene expression analysis indicates that the endometrium has the necessary functional characteristics to receive the embryo.

• Non-receptive: The implantation window is displaced, and the timing of embryo transfer must be adjusted according to the recommendations provided by the ERA test.

The ERA test is performed by simulating a transfer cycle, which consists of the following phases:

1. Phase 1: Endometrial preparation through the administration of estrogens and progesterone.

1. Phase 2: Endometrial biopsy. A tissue sample is collected at the moment in the cycle corresponding to the embryo transfer timing.

1. Phase 3: Sample analysis in the laboratory using mass sequencing.

When Is the ERA Test Recommended?

• In cases of recurrent implantation failure with high-quality embryos.

Although controversy remains regarding the effectiveness of this test, in select cases, it can help personalize the optimal timing for embryo transfer.