How are the results of the non-invasive preimplantation genetic test interpreted?
The results of the non-invasive preimplantation genetic test (NIPT) are interpreted by analysis of the embryo’s free cells or amniotic fluid.
This test seeks to detect genetic alterations in the embryo before its transfer to the uterus.
NIPT results are expressed as a probability or risk relationship, and are often interpreted by a clinical geneticist. The results may indicate a chance that the embryo has a specific genetic disease, such as Down syndrome, or may indicate an increased risk of some general genetic disease. In any case, it is important to remember that a positive result does not necessarily mean that the embryo has the disease, but only indicates an increased risk.
NIPT results should be interpreted along with other clinical and laboratory factors before making a decision about embryo transfer. It should be noted that this non-invasive study is in the experimental phase so its routine clinical application cannot be recommended.