Letrozole: The Best Alternative for Inducing Ovulation in Women with Polycystic Ovary Syndrome

10 / 07 / 2014

A study led by Richard Legro and published in the New England Journal of Medicine compared the medications letrozole and clomiphene to determine which is more effective in women with polycystic ovary syndrome (PCOS) who are trying to conceive.

The most commonly used medication for this group of women is clomiphene citrate (Omifin®); however, its success rate is lower (19%) compared to letrozole (27.5%) after six cycles. The twin pregnancy rate is also higher with clomiphene (6.9%) than with letrozole (3.9%). Furthermore, side effects are less frequent with letrozole than with clomiphene. Importantly, neither of the two medications poses any risk to newborns.

Leave a Reply 814 Comments
Leave a Reply
We receive many queries and it is not possible for us to provide a personal response to all comments. We will try to answer as soon as possible. In the meantime, we invite you to check our FAQ in case they can help you.
* This is a required field