What Are the Symptoms of Low Progesterone Levels?

Progesterone plays a crucial role in regulating the menstrual cycle and supporting pregnancy. During the second part of the menstrual cycle (the luteal phase), progesterone prepares the endometrium for a proper embryo implantation.

After implantation, progesterone helps develop the endometrium, relaxes the smooth muscles of the uterus, and suppresses immune activity at the uterine level to prevent the rejection of the embryo. Otherwise, the mother's antibodies could attack the embryo, preventing its development.

During the early stages of pregnancy, progesterone secretion depends directly on the corpus luteum, which remains in the ovary after ovulation. As pregnancy progresses and the placenta develops, it gradually takes over hormone production functions.

There are many causes of low progesterone levels in women, most of which are related to ovulation problems. Some common causes include:

  • Anovulatory cycles, meaning cycles where ovulation does not occur
  • Polycystic ovary syndrome (PCOS)
  • Hypothyroidism
  • Elevated prolactin levels
  • Menopause
  • High stress levels

Women with low progesterone levels may experience symptoms such as irregular menstrual cycles, sudden mood swings, irritability, and – in case of pregnancy – an increased risk of miscarriage or ectopic pregnancy.

For this reason, ensuring adequate progesterone levels during pregnancy is essential, and it is often administered in assisted reproduction treatments. Various progesterone supplements are available in oral, vaginal, or injectable forms. Qualified medical personnel will provide the supplement that best suits your personal condition, based on a personalized analysis of your case.
We help you answer your questions